Osteomalacia (rickets), which causes bones to soften, and osteoporosis are bone diseases that endocrinologists diagnose and treat. Osteoporosis is a disease that weakens your skeleton. Certain hormones act to protect bone tissue. When hormone levels are abnormal, bones can lose calcium and weaken. Menopause, in women, and loss of testicle function, in men, and aging may put you at risk for bone fractures. Endocrinologists treat other disorders that can affect bones, such as too much parathyroid hormone and long term use of steroids like prednisone.